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Varicocele
Varicocele occurs in 19 to 41% of infertile men and is considered the most common cause of male infertility. The exact mechanisms by which varicocele affects male fertility are still unknown. Recent data indicate a negative impact of increased DNA damage on male fertility potential.
Varicocele
Varicocele is found in 19 to 41% of infertile men and considered as the most common cause of male infertility. The exact mechanism(s) by which varicocele affects male fertility is still unknown. Recent data indicate a strong negative impact of increased DNA damage on the fertility potential of men.
Clinical Study for Varicocele
Zini showed a decrease in %DFI after varicocele surgery. Hum Reprod. 2005.20:1018-21
Clinical Study for Varicocele
Zini showed decreases in %DFI after varicocele repair. Hum Reprod. 2005. 20:1018-21
Can Sperm DNA Fragmentation Determine the Need for a Varicocelectomy?
Effect of microsurgical varicocelectomy on telomere length, DNA fragmentation and sperm
parameters Sandra Lara- Cerrillo et al (2020)
Below is an example of a patient in whom sperm DNA fragmentation decreased after varicocele repair:
Can sperm DNA fragmentation guide the need for varicocelectomy?

Microsurgical varicocelectomy effect on sperm telomere length, DNA fragmentation and seminal parameters
Sandra Lara-Cerrillo et al (2020)

Below is an example of a patient where there was decrease in the sperm DNA fragmentation after varicocele repair:

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